Arava: What It Is, How It Works, and Alternatives You Should Know

When you’re dealing with Arava, a disease-modifying antirheumatic drug (DMARD) used primarily to treat rheumatoid arthritis. Also known as leflunomide, it doesn’t just mask pain—it slows down the immune system’s attack on your joints. Unlike painkillers that give temporary relief, Arava works at the root cause, helping prevent long-term joint damage in people with moderate to severe rheumatoid arthritis.

Arava is part of a larger group called immunosuppressants, medications that reduce immune system activity to control autoimmune conditions. It’s often prescribed when simpler drugs like methotrexate or NSAIDs don’t cut it. But it’s not the only option. Other rheumatoid arthritis medications, including biologics and JAK inhibitors, offer different ways to calm inflammation—some faster, some with fewer side effects. The choice depends on your symptoms, other health issues, and how your body responds.

People on Arava need regular blood tests because it can affect the liver and lower white blood cell counts. It’s also not safe during pregnancy—both men and women must use birth control while taking it and for months after stopping. Many switch to alternatives like methotrexate, sulfasalazine, or newer drugs like adalimumab when side effects become too much. Others combine it with low-dose steroids for better control. What works for one person might not work for another, which is why so many posts here compare Arava to other treatments, lay out real-world experiences, and break down the trade-offs.

You’ll find detailed comparisons here between Arava and other arthritis drugs, including how they stack up in cost, effectiveness, and safety. There are also guides on managing side effects, what to expect in the first few months, and how to talk to your doctor about switching. Whether you’re newly diagnosed or have been on Arava for years, this collection gives you the clear, no-fluff facts you need to make smarter choices.