If stimulant medicines (like methylphenidate or amphetamines) aren’t a good fit, non-stimulant ADHD treatments can still help you focus, control impulsivity, and improve daily functioning. These drugs work differently from stimulants, often have a lower risk of misuse, and can be better for people with anxiety, tics, heart concerns, or a history of substance use.
Atomoxetine (brand name Strattera) — a selective norepinephrine reuptake inhibitor. It can reduce core ADHD symptoms but often takes 4–8 weeks to show full effect. Watch for decreased appetite, sleep changes, or nausea. Your doctor may monitor liver health in some cases.
Guanfacine extended-release (brand name Intuniv) — originally a blood pressure drug, it calms impulsivity and hyperactivity. It can make you sleepy at first and may lower blood pressure or heart rate. Dosage is usually started low and increased slowly to find the right balance.
Clonidine extended-release (brand name Kapvay) — similar to guanfacine, useful for hyperactivity and sleep problems tied to ADHD. Common side effects are drowsiness and dry mouth. Don't stop clonidine suddenly; that can raise blood pressure.
Viloxazine extended-release (brand name Qelbree) — a newer option that targets different brain systems. It shows benefit for attention and impulsivity and may be an alternative when other non-stimulants aren’t tolerated. Expect your prescriber to discuss potential side effects and how quickly it might work.
Other medications — some antidepressants (like bupropion) are used off-label for ADHD. They can help with attention and mood but may not be first-line non-stimulant choices.
Talk openly with your prescriber about goals: better focus at school or work, fewer outbursts, or better sleep. Expect a trial period where dose adjustments are common. Non-stimulants usually take longer than stimulants to work. If you don’t notice change after several weeks, check back with your clinician rather than switching meds immediately.
Monitor side effects closely: sleepiness, appetite change, mood shifts, and any cardiovascular symptoms. For children, caregivers should track behavior and school performance. Regular follow-ups help catch problems early and adjust dose safely.
Combine medicine with behavioral strategies. Medication often works best alongside therapy, structure, and sleep and exercise habits. Simple changes — consistent sleep, short task lists, and frequent breaks — make a big difference when paired with meds.
Cost and access: insurance coverage varies. Ask your prescriber about generic options, patient assistance programs, or pharmacist advice on savings. If you’re considering online pharmacies, use verified sources and keep your prescriber in the loop.
If stimulants aren’t an option, non-stimulant ADHD treatments give you useful alternatives. Work with your clinician, track results, and be patient — finding the right plan takes time but can change daily life for the better.
Strattera (atomoxetine) stands out from typical ADHD meds because it's not a stimulant. This article digs into how Strattera works, what sets it apart, the ups and downs of taking it, and what life looks like using this medication. With practical tips, clear info on side effects, and a candid look at common questions, you'll get all the details you need if you're considering Strattera or just want to know how it compares.