Strattera side effects: what to expect and how to stay safe
Strattera (atomoxetine) treats ADHD without being a stimulant. That’s a big plus for some people — but it also has its own set of side effects. Below I’ll walk you through the common reactions, the rare but serious risks, and simple steps you can take to reduce problems while on Strattera.
Common side effects and practical tips
The most common issues people report are dry mouth, sleep problems, stomach upset, and decreased appetite. These usually start in the first few weeks and often get better as your body adjusts. Simple fixes can help: chew sugar-free gum for dry mouth, take the dose earlier if it disrupts sleep, eat small snacks if your appetite drops.
Other frequent effects include dizziness, mild headache, and mood swings. If you notice dizziness, rise slowly from sitting or lying down. For headaches, try hydration and over-the-counter pain relief after checking with your prescriber.
Serious warnings you should not ignore
Though rare, Strattera can cause serious problems. It can raise blood pressure and heart rate — so your doctor should check these before and during treatment. If you feel chest pain, severe shortness of breath, or fainting, get medical help fast.
Another important concern is mood changes. Some people, especially children and teens, may develop increased anxiety, agitation, or thoughts of self-harm. If you or a family member notices new or worsening depression, suicidal thoughts, or aggressive behavior, contact your prescriber immediately or seek emergency care.
Strattera can also affect the liver in uncommon cases. Watch for dark urine, yellowing of the skin or eyes, or unexplained stomach pain — these are reasons to stop the drug and call your doctor.
Before starting Strattera, tell your provider about heart problems, high blood pressure, liver disease, or a history of bipolar disorder. Also mention other medicines you take, including over-the-counter drugs and supplements, because some can interact with atomoxetine.
Pregnancy and breastfeeding are special cases — discuss risks and alternatives with your doctor if you’re pregnant, planning pregnancy, or nursing.
How to track side effects: keep a short daily note for the first month. Write down sleep quality, appetite, mood, and any new symptoms. This simple log helps your doctor decide if the medication is right or if the dose needs adjusting.
Want to reduce risks? Start at the prescribed dose, attend follow-up visits, and don’t mix alcohol heavily with Strattera. Never stop suddenly without talking to your clinician — they’ll advise the best tapering plan if needed.
If you’re unsure about a symptom, call your prescriber. Small issues can be managed early, and the right monitoring makes Strattera a safer option for many people with ADHD.